Ms. Rothe studied molecular biology at the Martin-Luther University in Halle. During her study she worked for one year at the John Innes Centre in Norwich in the department of development. In 2007 she did her diploma thesis about the regulation of ion homeostasis in Saccharomyces cerevisiae at the IBMCP in Valencia. In 2008 Ms Rothe started her PhD in the department of Forensic Genetics at the institute of Legal Medicine in Berlin. During her PhD she specialized in different DNA extraction methods, in particular on the specific extraction of haplotypes from DNA mixtures and the DNA extraction from skeleton remains. In the last three years Ms Rothe established different ancient DNA extraction assays, which could be successfully used for the DNA extraction from archaeological and forensic cases.
Oct 2008 – Apr 2014: PhD in Forensic Genetics (Humboldt University of Berlin)
Oct 2001 – Nov 2007: Diploma in Biology (University Halle)
Selected project work
Dec 2006 – Sept 2008 Diploma in Valencia/Spain, Instituto de Biología Molecular y Celular de Plantas (IBMCP), University Politécinca: „Physiological characterization of yeast mutants lacking the protein kinases Hal4 and Hal5“
Apr 2005 – Mar 2006 Project in Norwich/UK, John Innes Center: Regulation of the cellshape by the MYB transcriptionfactor MIXTA in Petunia hybrida und Antirrhinum majus
Aug 2008 – present Institute for Forensic Genetics Charité, Institute for Legal Medicine, PhD Forensic Genetics
Rothe J, Nagy M. Comparison of two silica-based extraction methods for DNA isolation from bones. Legal Medicine. 2016;22:36-41.
Rothe J, C Melisch, N Powers, M Geppert, J Zander, J Purps, B Spors, and M Nagy. „Genetic Research at a Fivefold Children’s Burial from Medieval Berlin.“ Forensic Sci Int Genet 2015,3(15): 90-7.
Rothe J, Nagy M. Separation of Y-chromosomal haplotypes from male DNA mixtures via multiplex haplotype-specific extraction. Forensic science international Genetics. 2015;19:223-31.
Rothe J, Watkins NE, Jr., Nagy M. New Prediction Model for Probe Specificity in an Allele-Specific Extension Reaction for Haplotype-Specific Extraction (HSE) of Y Chromosome Mixtures. PLoS One. 2012;7:e45955.
Rothe J, Nagy M. Strategies for excluding false Y-chromosomal SNP entries from human genome databases. Electrophoresis. 2012;33:1488-91.
Rothe J, Roewer L, Nagy M: Individual specific extraction of DNA from male mixtures-First evaluation studies. Forensic Sci Int Genet. 2011,5(2):117-121
Geppert M, Rothe J, Willuweit S, Nagy M, Roewer L: Geografische Herkunftsbestimmung unbekannter DNA-Spuren.Rechtsmedizin, 2010, 20(4):270-274.
Perez-Valle J, Rothe J, Primo C, Martinez Pastor M, Arino J, Pascual-Ahuir A, Mulet JM, Serrano R, Yenush L: Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism. Eukaryot Cell, 2010,9(12):1881-1890.